New drugs for treating diseases of Down syndrome. More than 1% of the global GDP is spent on nursing demented people, and the number requiring nursing will triple within 2050. The disease is progressive, leading to death. There is no current cure available, only symptomatic treatments. Individuals born with Down syndrome have a more than 10x risk of developing dementia as well as a host of other diseases including diabetes. Our drug target, DYRK1A is an enzyme found on chromosome 21, and is considered a key factor determining developmental and medical challenges faced by individuals with Down. The enzyme interacts with multiple biological mechanisms involved in Alzheimer’s and autoimmune diseases. Advanced drug designUsing advanced drug design technologies, we have designed a potent DYRK1A inhibitor drug, PST-900. A use and substance of matter patent have been applied for. The company is currently working on chemical Lead Optimisation with 8 full-time medicinal chemists contracted.Financing and milestonesThe Company raised NOK 5 million in 2015 and 8.8 MNOK in 2016/2017, matching non-dilutive research (BIA) and business grants (Innovation Norway). We demonstrated Proof of Principle in a model system for Alzheimer’s disease in 2Q2016. We have also demonstrated that our drug is capable of reversing diabetes in an animal model. Together with clinical and regulatory advisors, we have identified an important unmet need for a drug to treat newly diagnosed diabetes. We will use this indication to quickly progress to market and from there develop analogous drug molecules in Alzheimer’s disease, focused especially in Down syndrome. Funding soughtThe current funding round will raise 15+ MNOK to fund the progression to the final Development Candidate during 2018. Following this, further funding will be sought to perform toxicology/safety and Phase 1 clinical studies. A highly experienced teamThe team behind Pharmasum Therapeutics have broad, international pharmaceutical and biotechnology experience, and is supported by an excellent group of advisors. Anders Fugelli, Ph.D., CEO. John Sigurd Svendsen, Ph.D., CSO. Pauline Stewart-Long, Ph.D. Project Management. Henning Mork, CFO. Board of Directors: Andrew Parsons, PhD. Øystein Soug, MSc. Mark Treherne, PhD, John Sigurd Svendsen, PhD.

Ecomerden is a complete producer of semi-closed cage systems for Aquaculture founded in 2012. With over 25 years of experience in delivering technology in the aquaculture industry, we started developing Ecomerden, a European patented semi-closed system for the lice-free production of fish. By 2015 the first cage was installed in Solund. Sogn & Fjordane. Here we have produced lice-free post-smolt of Atlantic salmon (90 grams-1kg) for 2 years with groundbreaking results. Using Ecomerden as a combination in the production line of the fish not only prevents lice pressure but also makes a more robust smolt ready for the open cages. With the results so far showing that the technology and biology are working, the company is now ready for commercialization.

Antibiotic resistance and bacterial infections are a large threat to modern healthcare. The Norwegian company SoftOx Solutions has developed a patented technology with the potential of becoming a game changer in fighting infections. To achieve this SoftOx has a highly competent organization and established a long-term relationship with leading scientists from the University of Copenhagen and Excite International, Canada. SoftOx wound cleansing solution shall become the first antiseptic with solid clinical evidence of infection removal in chronic wounds, giving us a unique market position in a 90 billion NOK wound care market.

We have now published the first version of the website Devent for Agility. The idea is to have a website where you can find agility-related information in the form of a meeting overview (list or calendar), results, annual overviews, and statistics for dog/organizer/judge (graphs are best viewed on a PC or landline phone). You manage which dogs you want to see statistics for easily on "my page". The system also has modules for setting up and running your own events and supports e.g. 5 size classes if desired. If you want to use the system for your event, you can read more and register here. We are still in an early phase and the system is under constant development. We are grateful for all constructive feedback, whether you experience errors or see things that should be solved in a different way. You will find a link for feedback here.

Wrepit is a Software-as-a-Service company with global ambitions, located in central offices in Oslo, Norway. With our software customers succeed with their written reports. They stay on brand, get quickly to market, and delight their readers with great readability, accessibility and interactivity on any device - even mobile. We are a young, growing company, and already have clients like KLP, Norconsult and Argentum.

Camping, local experiences combined with sociality, sustainability and closeness to nature is a growing area. The Norwegian camping industry has however an old-fashioned reputation and is very ripe for development. The majority of Norwegian campsites are family businesses, with limited capacity and resources for business development. Topcamp is building a camping business chain, mainly by buying or incorporating existing campsites with untapped potential and modernizing, streamlining and to a much greater extent digitizing the business. The previous owners of sites most often become partners in the process. Topcamp combines traditional core values such as good hosting, high-quality facilities, a rich range of activities and experiences – with modern business operations, technological operation and management tools.

We’re building a sustainable and fast internet by building a global, faster and more efficient website hosting infrastructure accessible to everyone. Servebolt is next level high performance managed hosting with a strong focus on scalability and security. We are technology leaders in the area of fast and scalable sites. We don’t follow “best practice”, we define what best practice is. Servebolt’s Platform equips customers with a suite of solutions that increase performance, scalability when building websites, stores and applications. Working at Servebolt is working in an informal atmosphere but with an extremely high professional approach on all facets of our services. It should come as no surprise independent tests were showing exactly that; Servebolt scoring the highest when it comes to scalability and performance.

Völur develops advanced AI models that optimize the use of raw materials in the meat industry, so customers create value by obtaining the most out of every animal and other scarce resources to satisfy market demand. Our disruptive tools are changing the meat industry from using traditional decision-making tools to using advanced AI models that recommend the most optimal and cost-effective production options

GreenStock’s cloud-based platform streamlines logistics for the reuse of building materials. Organisations can use the platform internally to map available materials in existing buildings and leftovers from building projects in a database for reuse in future construction projects. This will reduce carbon emissions as well as overall building costs. In future, GreenStock will be offered as a digital marketplace connecting buyers and sellers of reclaimed materials to reduce waste in commercial and residential construction projects. Concrete benefits Streamlined management of building materials can reduce construction waste, while cutting the costs associated with wasting new materials. GreenStock’s digital platform enables users to save materials, manage transport and storage, and gather documentation about the materials. It also provides data on the carbon reductions and financial savings generated through use of the platform. Materials that can generally be recycled from construction sites include steel and concrete elements, aluminium, untreated timber, cardboard, paint and plastics. Leftover materials may include complete products, such as doors, windows, insulation, flooring and technical equipment. Market potential GreenStock has completed development of the beta version of the platform and is testing it together with building developers. A fully developed solution for a public marketplace will be available by the end of 2020. The company is a member of NTNU Accel, an accelerator programme at the Norwegian University of Science and Technology (NTNU). GreenStock is targeting the Norwegian construction market which represent an annual revenue of NOK 466 billion (roughly USD 53.4 billion), Norway’s largest building suppliers which represent an annual revenue of NOK 29 billion (roughly USD 3.3 billion), as well as the home renovation market representing NOK 76 billion (roughly USD 8.7 billion). Around 10 per cent of materials from all building projects in Norway have the potential for direct reuse.

Flexistore is a Norwegian tech startup which offers the first fully digital self storage solution in the region. Our customers can easily book their storage unit in our app and get immediate access with digital keys to our modern facilities in Oslo city centre. Through continuously updating our functions with innovative technology, we encourage more sharing, recycling and reuse of the things you do not use every day.

STRATEGY TOOLS Strategy Tools is busy building the Modern Strategist Platform. We run a global strategy platform with users in 100+ countries. Our customers are accelerators, strategy directors, top management, business schools, innovation clusters and more. We already have customers in 60+ countries and we love what we do.  We are based in Stavanger,  but happily work remotely and travel globally. You  can too, if you join us, work from anywhere. Seriously. We look forward to connecting with you.

Oslo-based Epigram specialises in computer vision and visual classification, developing cutting edge tools and software to collect and analyse big data, with an acute focus on the application of AI to understand content. The company, founded in 2017, worked with multiple clients, including Huddly, Gjensidige, Tradono, and No Isolation to develop bespoke artificial intelligence and machine learning solutions.

The Core AS est. in 2015, innovates in the mid-market hospitality sector, opening restaurants Koie Ramen, Way Down South, Gressholmen Kro, and Night Pig. We are looking for talented individuals who know what it means to hustle! We are go-getters, doers, creatives, energetic, and passionate about food.

Our creative team have made a  cloud based system and an app called easy@work. It is a Workforce Management System that provides leaders with all necessary information to run their business at the best. Employees will get more self going and will have full insight and their workday is 100% transparent. In our own eco system you can produce and controll your Schedules, salaries, internal communication, checklists, personalfiles and more. Our platform is flexible and suited for all types of companies

Moonwalk designs startup challenges organised as programs. Alone or together with a strategic or financial partner. A program creates startups and runs for two semesters with paying participants. Then the program is incorporated. With participants as sweat equity part owners of the entire portfolio. An equity crowdfunding campaign decides how many startups are launched. Moonwalk is a 100 days startup hatcher and accelerator. No one should work here for any other reason than that they really want to. I had to figure out a way to fund and source the competence of people, but also fund their activity so that we can share in the outcome. No one had really given me any pointers on how to do that, so I had to find a new model of crowdfunding, crowdsourcing and shared ownership. Me and my colleague Victor developed that over the course of two years. He was a previous customer and the most talented person I know in the areas of value-chains and complexity. I asked him to join me and he said yes. We are in this together.