Lead Hardware System Architect

Salary €5,000 - €7,000
Equity To be negotiated

Lead Hardware System Architect — Proteins.1 | Espoo/Helsinki, Finland

Proteins.1 is building the PCR for Proteins — a novel diagnostic platform that detects disease biomarkers at the single-molecule level. Backed by Lifeline and Cloudberry Ventures, we are transitioning from deep-tech research to a commercial medical device. We have the biology, the IP, and newly established independent labs. Now we need the hardware leadership to bring it all together.

The Role

We are looking for an exceptional Hardware & Systems Lead to join our founding team and architect the electronic control and embedded systems for our breakthrough diagnostic instrument. You will own the full electronics and control stack — from mixed-signal hardware design through embedded firmware and FPGA logic — orchestrating our optical, microfluidic, and assay subsystems into a production-ready platform that outperforms benchmark systems in stability, scalability, and manufacturability.

What You'll Do

Architect: Own system-level hardware design covering front-end electronics, power tree, digital control, firmware/FPGA interfaces, and external connectivity.

Design & develop: Create mixed-signal and high-voltage boards with precision analog front-ends, level shifting, protection circuitry, and low-noise measurement paths.

Engineer & implement: Design and verify HDL/FPGA logic (VHDL/Verilog/SystemVerilog) for timing-critical sequencing, high-speed interfaces, and integration with ADC/DAC and sensor/actuator arrays.

Integrate: Work closely with photonics, microfluidics, and mechanical teams to co-design interfaces, synchronization schemes, and data paths across subsystems.

Who You Are

You are a rigorous hardware leader with 5+ years of experience in mixed-signal, high-voltage, and embedded electronics for complex instrumentation. You have a proven track record taking hardware from architecture and PCB design all the way through firmware and FPGA implementation, bring-up, verification, and transfer to production. You have deep expertise in multilayer PCB design for dense, connector-rich systems and FPGA-based control of matrix-addressed actuator or sensor substrates. Critically, you have shipped hardware products — not just built prototypes — and you approach every design with reliability and testability as first principles.

How We Work

We are serial entrepreneurs with backgrounds spanning drones, space, AI, biotech, and medtech — from R&D through globally shipped hardware and software products. There is no legacy architecture to inherit. You choose the stack, the tools, and the standards. As the product matures, you will grow your team by bringing in specialists to build on your foundation. We are based in Espoo/Helsinki and value in-person, high-bandwidth collaboration — relocation support is available.

Why Join

This is not a tinkerer role. You will own the entire electronics and control stack for an instrument platform with the potential to change how diseases are detected worldwide. It is a high-ownership, high-equity founding position in a company with strong science, a granted IP portfolio, and a team that prizes intellectual honesty and reproducibility over hype.

You will work directly with Harri, who previously built and exited a regulated active implant company to a US medtech giant, and Tuan Nguyen, who designed, scaled, and industrialized the highest-throughput chips for top biotech and pharmaceutical companies in drug discovery.

Apply by sending a brief description of the best hardware system you've built — and are proud of — to Tuan.

For more information or questions please contact us at tuan@proteins1.com or phone number +358 40 6411725

Perks and benefits

This job comes with several perks and benefits

Near public transit
Near public transit

Pension plan
Pension plan

Free office snacks
Free office snacks

Paid holiday
Paid holiday

Maternity / paternity leave
Maternity / paternity leave

Remote work allowed
Remote work allowed

See all 16 benefits

Working at
Proteins.1

Proteins.1 is a Finnish biotech startup on a mission to make diseases detectable years before symptoms appear — when treatment is most effective and survival rates are highest. The Problem For diseases like cancer and Alzheimer's, the body releases early warning proteins into the bloodstream long before any clinical symptoms emerge. The problem is that these signals are so faint that today's blood tests simply cannot detect them. By the time a diagnosis is made, the disease has often already progressed to a stage where treatment options are limited and outcomes are far worse. Our Solution We've developed a breakthrough technology called Affinity-Mediated Transport (AMT) — think of it as bringing PCR-like amplification to proteins. Just as PCR revolutionized the detection of genetic material, our platform makes individual disease-signaling proteins visible from a standard blood sample, at sensitivities up to 1,000 times beyond what current gold-standard diagnostics can achieve. The technology originated at VTT Technical Research Centre of Finland, has been validated through EU breakthrough innovation funding, and is protected by granted patents in both the EU and the US. Where We Are Founded in 2025 and backed by €4.7M in pre-seed funding from Lifeline Ventures and Cloudberry Ventures, we are a team of deep-tech founders, engineers, and scientists based in Espoo, Finland — building the next generation of diagnostic instruments that could fundamentally change how the world detects and treats serious disease.

Read more about Proteins.1

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